Irf7 molecular weight
WebIRF-7 plays an essential role in the induction of type I interferon in response viral infecton (6-8). Like IRF-3, IRF-7 is regulated at multiple serine phosphorylation sites near its carboxyl terminus, which are required for nuclear translocation, DNA binding, and transcriptional … WebFeb 2, 2024 · Despite the production of IRF7 fragments of lower molecular weight in ectopic expression systems of IRF7 A280GfsX12 ( Fig. 2 A ), we detected no IRF7 in the cells of patients P6 or P7 after stimulation with IFN-β ( Fig. 3 A ).
Irf7 molecular weight
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WebIRF7, once induced, is present in the cytoplasm as an inactive protein that is also phosphorylated on specific C-terminal residues by TBK1 and/or possibly IKKε kinases ( … WebPartial IRF7 recombinant protein (127-503 a.a.) Formulation This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. ... 503 amino acids, predicted molecular weight of 54 kD, contains an IRF tryptophan pentad repeat responsible for DNA binding Distribution Shuttles between the cytoplasm and nucleus ...
WebIRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional … WebPartial IRF7 recombinant protein (127-503 a.a.) Formulation This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Preparation Affinity …
WebApr 14, 2011 · IRF7 is a lymphoid-specific factor, which is constitutively expressed in the cytoplasm in B cells, pDCs and monocytes in the spleen, thymus, and peripheral blood … WebJul 7, 2024 · STING ∆CTT mice harbor a STING protein of the expected (decreased) molecular weight. ... It remains possible that IRF7, a homolog of IRF3, compensates for …
WebOct 15, 2012 · Wuhan University, Wuhan, China; 3National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ... IRF7 knockout mice displayed decreased weight gain and adiposity on a HFD. A: the comparison of body weight gains in WT or irf7 / (KO) …
WebIRF7-mediated control of the Gbp2 gene required the presence and basal activity of the S/T kinase TANK-binding kinase 1 (TBK1), whereas the binding of IRF7 to the Gbp2 promoter … raynaud\\u0027s toes treatmentWebAnti-IRF7 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA Research Category: Inflammation & Immunology Research Sub-Category: Immunological Signaling Gene Symbol: IRF7 UniProt Number: Q92985 View Products on Sigmaaldrich.com ABF202 100 µg Price could not be … raynaud\u0027s with gangreneWebJan 25, 2016 · IRF7 is a putative molecular driver of HBE responses to HRV. Differentially expressed genes were identified in HRV-induced HBE cells (Fig. 2 ), and then the wiring diagram of the IRF7 gene network was reconstructed from these data employing experimentally supported findings from published studies. raynaud\u0027s ultrasound protocolWebAnti-IRF7 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. CoA References Brochures Technical Information Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: Irf7 UniProt Number: P70434 ABF130 100 µL raynaud\u0027s underlying diseaseWebApr 4, 2024 · Interferon regulatory factor 7 (IRF7) is a direct target of miR-762 and overexpression of miR-762 reduced expression of IRF7. Data indicate that the type-I … raynaud\u0027s treatment calcium channel blockersWebNov 20, 2024 · IRF7 polymorphisms, like IRF5, ... in the Pharma industry since enzymes have catalytically active sites that are more readily accessible by small molecular weight compounds. Another possibility is the targeting of phosphatases that lead to the deactivation or inhibition of IRF5. These include A20 ... raynaud\u0027s white fingerWebPartial IRF7 recombinant protein (127-503 a.a.) Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) ... 503 amino acids, predicted molecular weight of 54 kD, contains an IRF tryptophan pentad repeat responsible for DNA binding Distribution Shuttles between the cytoplasm and nucleus; activated ... raynaud\\u0027s underlying disease