Sm-a-actin

Webb5 feb. 2024 · Actins是球状多功能蛋白质的一个家族,形成微丝。 ACTA2是6种不同肌动蛋白亚型之一,参与平滑肌的收缩。 ACTA2(和所有actins一样)极其保守,几乎在所有哺乳动物中都有发现。 在人类中,ACTA2由位于10q22-q24的ACTA2基因编码。 该基因突变导致多种血管疾病,如胸主动脉疾病、冠状动脉疾病、中风、烟雾病和多系统平滑肌功能障 … WebbDownload scientific diagram SM a -actin – positive TSC2-null lesions show mTORC1 activation, increased VEGF-D, and lymphangiogenesis.

Characterization of an E-boxâ Dependent cis Element in the …

WebbSMC-specific marker genes including SM a-actin, SM myosin heavy chain, SM22, h-caldesmon, calponin, and telokin. The CArGs within any given SMC-specific promoter are … WebbActin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells ( PubMed: 29581253 ). Actin exists in both … ch j articulation https://mikebolton.net

Developmental changes in isoactin expression in rat aortic …

WebbA smooth muscle antibody (SMA) is a type of antibody known as an autoantibody. Normally, your immune system makes antibodies to attack foreign substances like … Webbwith the Rho kinase inhibitor Y-27632 (10 mM) or actin polymerization with latrunculin B (0.5 mM) significantly decreased the activity of SM22 and SM a-actin promot-ers. In contrast, increasing actin polymerization with jasplakinolide (0.5 mM) increased SM22 and SM a-actin promoter activity by 22-fold and 13-fold, respectively. Webb21 mars 2024 · GeneCards Summary for ACTA2 Gene. ACTA2 (Actin Alpha 2, Smooth Muscle) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Aortic Aneurysm, Familial Thoracic 6 . Among its related pathways are Actin Nucleation by ARP-WASP Complex and Integrin Pathway . ch jaswant lal public school

UniProt

Category:Smooth muscle 22 alpha protein inhibits VSMC foam cell ... - Nature

Tags:Sm-a-actin

Sm-a-actin

Anti-alpha smooth muscle Actin antibody (ab5694) Abcam

Webbα-Actinin 属于细胞骨架蛋白的血影蛋白家族。 它最早被确认为肌动蛋白交联蛋白,在每个单体的氨基末端与肌动蛋白结合头形成反向平行同型二聚体。 α-actinin 可以与大量参与 … Webb15 jan. 1992 · Addition of sequence between positions −151 and −257 (p257CAT) resulted in a 7-fold increase in chloramphenicol acetyltransferase activity over that of p151CAT in rat SMC, but not in chicken SMC. A genomic clone encoding the rat smooth muscle alpha-actin gene was isolated, and the 5'-flanking region was partially characterized.

Sm-a-actin

Did you know?

WebbThermo Fisher nonmuscle beta actin emdb emd 27572 arora as huang hl heissler sm chinthalapudi k 2024 cryo em structure Nonmuscle Beta Actin Emdb Emd 27572 Arora As Huang Hl Heissler Sm Chinthalapudi K 2024 Cryo Em Structure, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. WebbAntibody 1A4 (DAKO) recognizes SM a-actin and was used to detect SMCs, whereas antibody HAM56 (DAKO) was used to recognize macrophages in the sections. Activin was detected with monoclonal antibody E4 (Serotec), and follistatin with an anti-peptide antibody (provided by Prof S. Werner, ETH, Zurich, Swit-zerland).

Webb22 okt. 2024 · Vascular smooth muscle cells (VSMCs) are indispensable components in foam cell formation in atherosclerosis. However, the mechanism behind foam cell formation of VSMCs has not been addressed. We ... WebbTransforming growth factor (TGF)-b-induced expression of smooth muscle (SM)-a-actin is accompanied by expression and activation of serum response factor (SRF). (A) Human …

WebbThe antibody (also known as anti-α-Sm-1) is specific for the single isoform of α-smooth muscle actin. It reacts specifically with α-smooth muscle actin in immunoblotting … WebbSee all alpha smooth muscle Actin primary antibodies Description Mouse monoclonal [1A4] to alpha smooth muscle Actin Host species Mouse Tested applications Suitable …

WebbStress may directly activate transcription of the α-SM actin gene, since application of force across integrin binding sites has been shown to up-regulate α-SM actin promoter activity. 52 As mentioned above, mechanical force alone is not generally sufficient to induce myofibroblast differentiation and other factors are needed to act in concert, specifically …

WebbThe Actin Alpha 2 (ACTA2) gene encoding smooth muscle aortic actin, was isolated and characterized. It was found that the ACTA2 gene contains at least 9 exons (7). Alpha smooth muscle actin appears to play an important functional role in myofibroblast contraction and migration. chjc canton nyWebbSM a-actin promoter is regulated through combinatorial interactions between different factors. Transforming growth factor-b induced activity of the 125-bp rat SM a-actin promoter is dependent on both an intact transforming growth factor-bcontrol element and intact CArG boxes.18 Addition-ally, the homeodomain factor MHox activates SM a-actin grass leander txWebbThe smooth muscle α-actin and γ-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. The α-smooth muscle actin (ACTA2) is … chj clinic buckinghamWebb1 jan. 2008 · Alpha-smooth muscle actin (alpha-SMA) is the actin isoform that predominates within vascular smooth-muscle cells and plays an … grass leafsgrass leatherWebbSmooth Muscle Actin ( Figures 25-3, A, and 25-4, A) The smooth muscle actin (SMA) marker has a relatively long track record of use as a myoepithelial marker in breast … chj3 architectureACTA2 (commonly referred to as alpha-smooth muscle actin or α-SMA) is often used as a marker of myofibroblast formation. Studies have shown that ACTA2 is associated with TGF-β pathway that enhances contractile properties of hepatic stellate cells leading to liver fibrosis and cirrhosis . Visa mer ACTA2 (actin alpha 2) is an actin protein with several aliases including alpha-actin, alpha-actin-2, aortic smooth muscle or alpha smooth muscle actin (α-SMA, SMactin, alpha-SM-actin, ASMA). Actins are a Visa mer • Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biologica. 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639. S2CID Visa mer • GeneReviews/NIH/NCBI/UW entry on Thoracic Aortic Aneurysms and Aortic Dissections • Human ACTA2 genome location and ACTA2 gene details page in the Visa mer grass leather jacket