Sox4 chip
WebHere, we focused on six sex determining region Y-related HMG-box (SOX) transcription factors (SOX4, 6, 8, 9, 10, and 11) highly expressed in TNBCs. Our siRNA screening assay … Web9. mar 2024 · The target sequence of the transcription factor Sox9 in IESCs was investigated via chromatin immunoprecipitation (ChIP) combined with deep sequencing (ChIP-seq). Increased Sox9 expression is accompanied by the loss of methylation in its promoter in IESCs. ... Sox4, and Fzd8, but also functions as a potential transcriptional inhibitor at a ...
Sox4 chip
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Web6. okt 2024 · Tbx3, SOX4, and SOX2 ChIP data, identify a region in intron 1 of Gja1 bound by all tree proteins and subsequent ChIP experiments verify that this sequence is bound, in vivo, in the developing heart. In a luciferase reporter assay, this element displays a synergistic antagonistic response to co-transfection of Tbx3 and Sox4 and in vivo, in ... Web为了了解sox4在动脉粥样硬化中的作用，在wd喂养前，将内皮特异性aav-sox4注射到apoe−/− 小鼠。结果表明，sox4过表达增加了apoe−/− 小鼠主动脉中sox4蛋白的表达（图2 a）。sox4过表达增加了apoe−/− 小鼠面主动脉和主动脉根部的病变区域（图2 b、c）。
Web10. nov 2008 · SOX4 is a critical developmental transcription factor in vertebrates and is required for precise differentiation and proliferation in multiple tissues. In addition, SOX4 is overexpressed in many human malignancies, but the precise role of SOX4 in cancer progression is not well understood. Here we have identified the direct transcriptional … Web21. mar 2024 · SOX4 (SRY-Box Transcription Factor 4) is a Protein Coding gene. Diseases associated with SOX4 include Intellectual Developmental Disorder With Speech Delay And Dysmorphic Facies and Coffin-Siris Syndrome 1 . Among its related pathways are Signaling by WNT and ERK Signaling .
Web21. mar 2024 · SOX4 (SRY-Box Transcription Factor 4) is a Protein Coding gene. Diseases associated with SOX4 include Intellectual Developmental Disorder With Speech Delay And …
Web15. jan 2009 · SOX4 is up-regulated by TGFβ-1 treatment , and we found SMAD4 sites are significantly enriched in the SOX4 ChIP-chip peaks , suggesting that SOX4 affects key …
WebInterestingly, ChIP-seq assays revealed that 70.4% of SOX4 peak summits were within 50bp of the RELA peak summits suggesting that both proteins bind in close-proximity on regulatory sequences ... makeup thesisWebEach SOX4 Antibody is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. Our SOX4 Antibodies can be used in a variety of model species: Human. Use the list below to choose the SOX4 Antibody which is most appropriate for your research; you can click on each one to view full technical details ... make up thesaurusWeb3. feb 2016 · Sox4 was also able to promote β-catenin-mediated transcription of the Slug gene through formation of transcriptional complexes with β-catenin and p300, independent of TCF4 status. ... e ChIP assay data showing that Sox4 is bound to Slug promoter regions, in particular after culturing in STK2 for 3 days. makeup theoryWeb3. máj 2011 · Tbx3, SOX4, and SOX2 ChIP data, identify a region in intron 1 of Gja1 bound by all tree proteins and subsequent ChIP experiments verify that this sequence is bound, in vivo, in the developing heart. In a luciferase reporter assay, this element displays a synergistic antagonistic response to co-transfection of Tbx3 and Sox4 and in vivo, in ... makeup theory step by stepWeb27. okt 2016 · A SOX4 ChIP time course using AG05811 adult fibroblasts provided insight into the varied genetic landscapes of adult and fetal fibroblast lines. SOX4 enrichment at sites identified by ChIP-seq in 1-DPT MRC-5 cells exhibited significantly delayed occupancy in adult cells through 4 DPT (Figure 6D). This suggests that condensed chromatin might ... makeup the sims 4 ccWeb22. apr 2024 · SOX4 and RELA Function as Transcriptional Partners to Regulate the Expression of TNF- Responsive Genes in Fibroblast-Like Synoviocytes SOX4 and RELA … makeup theme party ideasWebChIP-qPCR, FAIRE assay and luciferase reporter assays were used to investigate transcriptional regulation. Results: SOX4 was identified as the main transcriptional effector of thermogenesis. Mice with either adipocyte-specific or UCP1 + cells deletion of SOX4 exhibited significant cold intolerance, decreased energy expenditure, and beige ... make-up - the voice from yesterday